Newcastle prop Kade Snowden will miss the Knights match against Brisbane because of post-concussion symptoms.

The key forward was placed in a neckbrace and lifted onto a motorised stretcher after being knocked out while trying to tackle Jarrod Croker in the 63rd minute of Newcastle’s 26-12 victory over the Raiders on Saturday. Adam Cuthbertson is expected to take Snowden’s place in the squad.  Rookie winger Jake Mamo will make his NRL debut for the Knights. Despite Newcastle coach Wayne Bennett naming Josh Mantellato to replace the injured Akuila Uate, Mamo trained with the Knights on Thursday. Brisbane's Sam Thaiday (calf) is in extreme doubt after he was unable to complete training on Thursday.

South Sydney will be without suspended duo Ben Te’o and George Burgess when they play a Canterbury side who will miss Frank Pritchard (pectoral) for the rest of the season.

Manly and North Queensland are expected to be unchanged for their clash at Central Coast Stadium on Friday night.

St George Illawarra’s Dylan Farrell will miss the rest of the season after rupturing a pectoral muscle in the Dragons' dramatic loss to Melbourne on Monday night. Joel Thompson is set to switch from the back row to the centres to cover for Farrell’s injury. The Warriors have dropped centre Konrad Hurrell.

The Sharks are hoping Anthony Tupou will play his first game of the year despite not being named. Tupou didn’t complete training with the squad on Wednesday and will need to pass a fitness test on Friday to play the Roosters on Saturday night. The Roosters should be 1-17.

Melbourne centre Will Chambers will miss the next two weeks after being hit with a grade-two shoulder charge. Mahe Fonua is his likely replacement to play the Raiders.

Darcy Lussick will play his first game for the Eels after a four-week suspension. At ANZ Stadium on Monday afternoon the Eels host a Tigers side who will be without the injured Robbie Farah (elbow). USA representative Joel Luani will replace Farah.

The Titans have Anthony Don (finger) and Will Zillman  (hamstring) in doubt. Zillman is hopeful of returning having missed the past three games when they travel to Penrith on Monday night.