The owner of an inner Sydney beauty clinic has died days after a botched procedure left her in a critical condition.
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Jean Huang, 35, was rushed to Royal Prince Alfred Hospital on Wednesday after she went into cardiac arrest at The Medi Beauty clinic in Chippendale.
Police said she died in hospital on Friday.
On Thursday, a police document tendered to Central Local Court alleged Jie Shao used the wrong dosage of anaesthetic during a procedure to put fillers into Ms Huang's breasts.
Ms Shao was visiting from China on a tourist visa, prosecutors told the court, and had no recognised qualifications in Australia.
Prosecutor Sergeant Rutzou said Ms Shao made admissions, in a police interview on Wednesday night, about administering anaesthetic during the procedure. He said police would upgrade charges if Ms Huang died.
Ms Shao allegedly administered 1?? grams of the opioid tramadol mixed with 200 milligrams of NaCl (sodium chloride) through a catheter and a drip, and additional amounts of a local anaesthetic, lidocaine, were injected into Ms Huang's chest.
Another employee, Yuegiong Fu, was working as a nurse during the procedure but is also not qualified, police alleged.
When Ms Huang went into cardiac arrest, Ms Fu and a third employee, Ronald Hsiao, attempted CPR.
Paramedics rushed to the clinic, however police told the court Ms Huang would suffer "some degree of brain damage", with grave fears for her survival.
Ms Shao, 33, had completed a five-year degree at Guangdong Medical University specialising in dermatology, the court heard.
She has been charged with recklessly causing grievous bodily harm and administering a poison.
Magistrate Sharon Freund denied Ms Shao bail, saying there was a risk she would flee to China, interfere with witnesses or endanger others in the community.
Ms Shao will face court again on September 5.
In a statement on Friday, police said they would continue to investigate the incident.
"Inquiries are continuing with a view to further legal action being considered," the statement said.
"Police are urging anyone with information in relation to this incident to call Crime Stoppers on 1800 333 000."
Ms Huang was the manager and co-owner of the newly-opened clinic, which is part of Sydney's Central Park development.
She previously lived in Melbourne, studying at The University of Melbourne, before opening the clinic in May.
She had also studied at the University of New South Wales.
